Plant disease is the main enemy of agricultural production. According to the Food and Agriculture Organization of the United Nations (FAO), the average annual loss of production due to plant diseases is 10% to 15%.At present, the main means of controlling plant diseases is chemical fungicides. However, due to potential human health hazards, environmental pollution, non-target organisms, and development of plant pathogen resistance, the development of chemical fungicide has been limited. Biological fungicide are attracting more and more people’s attention and interest.
Bio-sourced fungicides refer to the direct use of biologically active substances produced by biological organisms or biological metabolic processes or substances extracted from organisms as a disease prevention and treatment. The concept of biological pesticides is vague and can be considered equivalent to biologically derived fungicides.According to statistics, there are more than 100 kinds of biological pesticides products in the world, but more than 90% are bio-insecticides. The next important commercial bio pesticide will be a bio fungicide.The bio fungicide currently developed are basically microbial fungicides of bacteria, fungi and antibiotics, mainly including agricultural antibiotics, bacterial fungicides, fungal fungicides and viral fungicides. Microbial fungicides mainly inhibit the energy production of pathogens, interfere with biosynthesis and destroy cell structure, have strong compatibility and low toxicity, others also have the effect of stimulating plant growth.
Agricultural antibiotic bactericides are secondary metabolites produced by microbial fermentation processes that inhibit or kill plant pathogens and regulate crop growth and development at low concentrations. For example, Kasugamycin, Jinggangmycin, Polyoxymycin and Streptomycin. At present, agricultural antibiotic fungicides are the leading force of biocides.
In recent years, people have gradually recognized the important role of Gram-positive bacteria in biological control. In particular, Bacillus spp. has a wide variety of resources and abundant resources. The formation of spores makes them adaptable and resistant to stress, easy to industrialize production and storage, and has great potential for application. Bacillus subtilis has a good control effect on the plant pathogenic bacteria Fusarium and Rhizoctonia, and at the same time has the functions of preventing disease and promoting crop growth.Because of the variety of bacteria, large quantities, rapid reproduction, and easy artificial culture and control, the research and development of bacterial fungicides has great prospects.
The most widely studied and applied fungal fungicides are Trichoderma spp. The inhibition of phytopathogenic fungi by Trichoderma has been discovered. It has good effect on resistance to various diseases such as blight, sclerotinia, pythium and botrytis. It has a good market prospect.
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