Under The Bridge by the Red Hot Chili Peppers is one of my favorite songs (especially the live versions), so naturally it came to mind when i was lining up this shot. I may or may not be listening to it as I write this. If you didn't hear it on the radio too many times to ever want to hear it again you can listen to it below.
The Ohio River, and more specifically the Falls of the Ohio, are the reason for Louisville's existence. Before the locks were built all river traffic had to stop at the falls, unload and portage to the other side of the falls, and reload aboard another boat. The city grew up around the trade from portaging and river traffic. Eventually locks were built that put an end to the portaging but by that time the city was growing nicely.
With the Ohio River defining its northern border, Louisville naturally has lots of bridges (counting the railroad bridges and the pedestrian one there's 9 total), which makes for lots of fun photography adventures. On a vaguely related note, Kentucky 'owns' the Ohio along its border, you're not out of the state until you cross the northernmost edge of the river.
I was on an adventure to the Big 4 Bridge, a former railroad bridge converted into a pedestrian bridge, when I took these photos. We walked over to Indiana and had a rather tasty meal (this was pre-Covid) and played with cameras for a bit before wandering back (there's ramps so you can also ride bikes across). It gets a bit windy up there so if it's a cool day you better be dressed warmly.
That's enough out of me, aside from an obligatory mention of @monochromes #monomad contest :)