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HGPRT enzyme (hypoxantin-guanyl phosporilbosyl transferase) which has a close relationship with purine as an ingredient of uric acid, Purine is one of the constituents of the DNA and RNA chains together with pyrimidine. The HGPRT enzyme is the task of converting purines into ourin nucleotides so that they can be reused as DNA and RNA compilers.
Purines contained in meat will be changed and rearranged into body proteins. This is the procedure for the body to get nutrition from meat. This purine conversion process involves the HGPRT enzyme. If the body is deficient or deficient in this enzyme, the amount of purine in the body will accumulate. Unused purines will eventually be converted into large amounts of uric acid. Finally we enter hyperuricemia. HGPRT enzyme deficiency is genetic. That is, there are mutations in the gene that encodes the HPGRT enzyme so that this enzyme is produced in small amounts.