Cancer diagnosis before symptoms appear? US researchers say eight types of cancer will be detected from a blood test.
Experts expect ovulation, liver, stomach, pancreatic, gastric, cerebral and tumor cancer and will only be detected in a blood test in the future. More importantly, when the blood tests are found in cancer, it did not spread or did not grow too much, that is, in the initial stage. This does not require chemotherapy, but in a small operation the tumor should be removed - before it can be spread.
For many years, scientists are looking for the so-called "liquid biopsy" - which means that blood tests of blood, without checking the body's cells, determine the presence of tumor. Even such screenings may be part of regular health checks. Scientists at John Hopkins School of Medicine at Baltimore published their results in the journal Science, and named the blood test called 'Cancer-Sick' (CancerSeeE).
DNA of blood cancer
When the body cells are cancerous, then there is genetic changes in the cells. In most cases, the cells change in such a way that the cells grow uncontrollably. When a tumor cell dies, its remains often go to blood - then it is possible to diagnose the presence of cancer-related genes and proteins. In the 'Cancer-Syc' test, eight protein and 16 genetic mutations were detected in the cancer cell.
Only eight types of cancer? In response to this question, the original author of the essay, Science, Joshua Poetry, said that due to the attention of a special group of so-called 'tumor markers', this will reduce the chance of showing 'positive' results in the test and the cost of the test will be low - finally Scientists expect this screening cost to be less than $ 500. However, it will still take some time to become part of this test routine checkup.
In case of ovarian cancer, more than breast cancer
Researchers examined blood samples of 1,005 patients with different levels of cancer. In this case, 70 percent of the cases were able to successfully diagnose cancer. In the case of approximately one-third of patients, this test failed to diagnose cancer.
Especially for breast cancer, only one in three patients is diagnosed with cancer.
On the other hand, 98 percent of tumors in the case of ovaries and liver cancer can be found in the 'Cancer-Sick' test.
More importantly, the 'cancer-sick' that can diagnose eight types of cancer, among which it is not possible to diagnose cancer in any other way, that is, cancer is not possible. However, in the colonoscopy of colon or colonization, the initial colon cancer can be detected initially.
Scientists have also tested blood tests of more than 800 people, as well as knowing how many ordeal results are being shown in the test. In the case of healthy people, only seven percent of cases - that is, 'positive' results showed 'cancer-sick' in just one percent of cases.
Yet the cancer experts warned against expecting more from this test. Especially in the early stages of tumor detection, 'cancer-sic' could detect less than half of the tumor. Only after having adequate amounts of cancer that can be detected in screening 'cancer-syc' - when other symptoms of the disease have already occurred - then the question of usefulness of this test can be questioned.
Experts fear that the possibility of 'positive' results in the 'cancer-sic' test may be more likely to result in a 'positive' result, because patients suffering from chronic disease or other diseases have been excluded from the examination. However, in cases of inflammation or inflammation the blood is often found in a protein that can be detected in the 'cancer-syc' test.
Therefore, more testing needs to be started and it has already started. Researchers from the Geiger's Health System and John Hopkins University of Pennsylvania.
source:Deutsche Welle Report