Hello all fellows ,

Today we talk about Polycystic kidney disease . There are two types of it.

1. Autosomal Dominent Polycystic kidney disease (ADPCKD)

2. Autosomal Recessive Polycystic kidney disease (ARPCKD)

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                   Pic: collected

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Clinical Symptoms :

• Asymptomatic most patients
• Hematuria ( Blood passing through urine )
• Pain on Flank ( infections, any cyst rupture, kidney stone, internal bleedings )

Clinical Signs :

• High Blood pressure (HTN)
• Proteinuria ( Protein passing through urine)
• Bilateral abdominal masses
• Chronic kidney/renal disease

Other Extrarenal features :

• Ventral and inguinal hernias
• Cardiac valves disorders ( Mitral valve prolapse, Aortic Regurgitation )
• Colonic diverticulosis
• Hepatic and pancreatic cyst
• Cerebral aneurysms

How to Diagnose:

*USG( Ultrasonogram mainly)
*CT scan( computed tomography), MRI (Magnetic resonance imaging )
shows multiple renal cysts

Treatment or Management :

• Continuous Blood pressure and renal function follow up.
• Hypertension control aggressively
• ACE inhibitors for high blood pressure
• In case of end-stage renal disease- Dialysis , renal transplant