FDA as expected approves Moderna and J&J boosters and heterologous boosters. Moderna's booster guidance is the same as Pfizer's booster. Six months after your second dose an adult can get a booster

Image - Agency R7 (Brazil). FDA authorizes Americans over 18 years to receive another dose of immunizer from two months of first application. *The immunizer should be given from two months of the first

Heterologous second doses were well-tolerated and effective. This trial didn't look at third dose boosters, but there is another trial looking at heterologous third dose boosters. I think I'll be getting

This graph conveys a lot of information in a compact way. This study directly compared antibody levels in various groups of people, including: Those who provided samples before the pandemic People with

Today J&J released an 8-month update study in a small subset of trial participants (8 people), including information on the delta variant. They chose an older subset ranging in age from 47-91, in order

Of interest to those who got J&J, an update on the people in the phase 1/2 trial was released yesterday. This early trial was a dosing study, so not everyone got the same dose as the one that eventually

FYI -- I did a quick search in VAERS for bell's palsy after covid vaccinations and came up with a possible signal for J&J. Looking specifically at the two-week window between two and four weeks after

ACIP didn't make a recommendation on J&J yesterday, but some useful background information was presented to contextualize things a bit more on the risks and costs. While 7.2 million doses of J&J

This has come up again with the J&J vaccine pause, but I'm curious how we should approach risk perception with vaccines and in general with public irrationality. Let me just preface if I was in charge

Don’t suspend the J&J vaccine. Suspend the FDA instead - at least until they demonstrate that they understand basic cost-benefit analysis. A course in basic moral philosophy might be useful, too. Every

The Pfizer and Moderna vaccines are mRNA vaccines. The mRNA is used by our cells to make virus proteins to create an immune response, not the whole virus. Then, the mRNA degrades. The Astra Zeneca and

Of course the worst looking state on this map is the one relaxing the quickest. Why would this pandemic year go any different than it has before? More on this later.. Biden is now saying we will have enough

Ahead of the VRBPAC meeting we got the briefing document for the J&J vaccine. It looks to be a pretty good vaccine, though some caveats. This one has a different primary efficacy endpoint than the

There are 59 million Americans aged 65 or older. ~80% of the COVID deaths in the US so far have been in this age group. Many parts of the US are now in a vaccination tier where anyone aged 65 and older

J&J's vaccine results came a bit earlier than expected. The most important thing to highlight is it was 85% efficacious on preventing severe disease after 28 days. At 49 days, there were no cases of