10 years is already long, and I think modern medicine has been really good at identifying risks and effects. They also check the person's overall health before prescribing it. If there are issues with the pancreas and other related organs then it isn't prescribed.

I think people put in the effort in all sorts of things. If you're asking about effort into exercising and discipline versus using ozempic to do more things they love, I think they will be glad that they took ozempic and got to enjoy their life more.