Most of the ones I've read says it's very safe.

They have only been used in any form for about 10 years - won't really know about long-term effects for another 20 or so.

It isn't even insulin, but encourages insulin production in the pancreas.

Remember that the pancreas is pretty fragile and non-replaceable.

The deathbed conversation is more about whether someone is glad they put in the effort, or glad they didn't. We all die.