Is it too early to say the male contraceptive pills available near future.
One of the medicine is of almost the same nature as contraceptive pills that females take once a day. According to the results of clinical experiments, it seems that medicine Dimethandrolone undecanoate became safe and effective for human subjects.
Researchers gave Dimethandrolone undecanoate to 100 healthy people aged 18 to 50 years old. Ingested different amounts orally with capsules containing castor oil or powder. During the experiments that took place for about a month, the subjects were told to take capsules with food once a day, as a result, 83 people finished taking it to the end.
End of the experiment, subjects who had ingested Dimethandrolone undecanoate had two types of hormones required for the production of testosterone and spermatozoa. However, it took about 3 months for the decreased hormone to significantly reduce the number of spermatozoa, so semen itself was not tested in this experiment.
Ms Stephanie Page, professor of medicine at Washington University, talk at the media conference this is a big step towards the development of contraceptive pills for men, excited about the results.
It was necessary to ingest at least twice a day from the poor absorption rate by oral. However, taking too much testosterone at one time puts a burden on the liver or side effects such as mood swings. The most recent experiment done in 2016 is to eliminate testosterone based contraceptive infusion experiments at an early stage. Because several of the men reported serious emotional side effects and one had committed suicide.
Ms. Page "The most important result for us was that none of the harmful side effects or signs were seen at all." The subject was able to accept the medicine very well, and side effects such as nausea commonly found in oral medicine it could not see a burden on the liver.
Some of the side effects that the research team could confirm were weight gain and loss of HDL cholesterol, good cholesterol. However, they think that they are symptoms that can be avoided by adjusting intake. The important thing is that there were no other long-term symptoms that should have occurred due to a reduction in testosterone. Eight of the patients who received treatment reported a decrease in sexual desire, but it seems that they gradually recovered after stopping treatment.
At this time, the research results that have not yet been published are the only hope. The research team is currently conducting trials over a three-month period, that is, using periods in which direct effects are known by counting the number of sperm.
