histamine nitrate metabolism Nitric oxide ammonia antioxidants ascorbate glutathione polyphenols potassium magnesium

https://www.verywellhealth.com/beet-juice-vs-pomegranate-juice-11837232

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it seems Beets have good (red) Nitrates, and Pomegranate has (red) Antioxidants, both increase the good Nitric Oxide levels.

so good vs bad Nitrates have Antioxidants included, plus magnesium & Potassium making them healthy Nitrates.

in the same way Antioxidants turn the bad into good oils, cholesterol & lipids.

deep fried greasy food & microwave knocks out the delicate antioxidants.

wonder if by adding the good parts back, will make bad food good again?

healthy plant superfoods are loaded with Magnesium & Potassium, along with Sulfates & Nitrates, appears Nitrogen & Sulfur require these mineral ions to operate correctly, the same goes for Vitamin C how it can turn into toxic Oxalate without balancing salt ions.

it appears the elements to all superfoods are Magnesium, Potassium, Ascorbate, MSM and Polyphenols.

cooking destroying them or binding the salt ions.

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Magnesium and potassium ions play critical, interconnected roles in cellular metabolism, antioxidant systems, and the regulation of nitric oxide and glutathione.

Histamine metabolism interacts with nitrate and nitric oxide (NO) pathways, influenced by various antioxidants and minerals, primarily through the regulation of inflammation and vasodilation.

Histamine and Nitric Oxide:

Histamine stimulates the production of NO by upregulating the gene expression and activity of endothelial nitric oxide synthase (eNOS) via the H1 receptor. NO, in turn, generally has a protective, inhibitory effect on mast cell histamine release, thus helping to regulate inflammatory responses and vasodilation. However, under conditions of oxidative stress, the histamine-induced eNOS can produce reactive oxygen species instead of NO, which can be harmful.

Nitrate and Nitric Oxide Metabolism:

Dietary nitrate is a major source of systemic NO via the enterosalivary pathway, where oral and gut bacteria reduce nitrate to nitrite, which is then further converted to NO in acidic environments like the stomach.

Ascorbate (Vitamin C), Glutathione & Polyphenols:

These are key components of the cellular antioxidant system, which is important for regulating hydrogen peroxide and protecting cells from oxidative damage. They are also effective antioxidants and can reduce lipid oxidation and N-nitrosamine formation in foods.

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Tyrosine
Pomegranate & Beets

Betalains are a class of red and yellow tyrosine-derived pigments

Betalains are red-violet and yellow pigments that are derived from the amino acid tyrosine through a biosynthetic pathway in plants. Tyrosine is the essential precursor, which is modified by enzymes to create betalain pigments like betacyanins (red-violet) and betaxanthins (yellow).

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Bicarbonate is synthesized industrially primarily through the Solvay process, which reacts brine with ammonia and carbon dioxide to produce sodium bicarbonate.

Magnesium potassium bicarbonate is a chemical compound that combines magnesium, potassium, and bicarbonate ions

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Sodium bicarbonate helps buffer these excess H+ ions, facilitating their transport out of the muscle cells and into the bloodstream where they are neutralized.

Sodium bicarbonate aids muscle recovery and performance by acting as a base to buffer exercise-induced acid (hydrogen ions), thus maintaining a more stable pH.

During high-intensity exercise, muscles produce hydrogen ions H+, leading to a drop in muscle pH (acidosis) and subsequent fatigue.

By delaying the drop in muscle pH, sodium bicarbonate can enhance muscle endurance and power.

The bicarbonate ions HCO combine with H+ ions to form carbonic acid H2CO3, which quickly breaks down into water H20 and carbon dioxide CO2, which is then expelled via the lungs.

the combination of vitamin C and sodium bicarbonate might enhance the body's overall antioxidant ability and upregulate protective proteins (heat shock proteins) in cells exposed to stress.

Exercise-induced anaphylaxis: Pretreatment with sodium bicarbonate has shown to prevent the reoccurrence of anaphylactic symptoms in individuals with exercise-induced anaphylaxis. It was observed to inhibit the blood pH decrease that accompanies the elevation of plasma histamine levels in these cases.