RE: RE: Intercellular Homeostasis
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RE: Intercellular Homeostasis

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Methylated Arginine
ADMA & L-NMMA

Asymmetric Arginine
Monomethylated Arginine
Methylated Arginine
Protein Degradation
Protein Detoxification

Arginine
Cysteine
Methylation
Dimethylargininase
Nitrosamine

Glutamine
Glutamate
Glutathione
Homocysteine

..

Polyphenol antioxidants also play a role in down-regulating homocysteine.

Nitrosamine formation during digestion

Methylated arginine metabolites that are produced from protein degradation

An excess of RNS (nitrosative stress) or reactive oxygen species (ROS) can impair vascular function. The reduction in NO bioavailability caused by ADMA accumulation is a key aspect of this dysfunction.

Elevated ADMA not only reduces NO production but can also induce the formation of more harmful oxidative and nitrosative species.

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Asymmetric dimethylarginine (ADMA)

Protein arginine methyltransferases (PRMTs)

https://en.wikipedia.org/wiki/Nitrosamine_formation_during_digestion

https://en.wikipedia.org/wiki/Asymmetric_dimethylarginine

https://en.wikipedia.org/wiki/Dimethylargininase

https://en.wikipedia.org/wiki/Protein_detoxification

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Oxalate, inflammasome, and progression of kidney disease

https://pmc.ncbi.nlm.nih.gov/articles/PMC4891250/

Acidosis and citrate: provocative interactions

https://pmc.ncbi.nlm.nih.gov/articles/PMC6186559/