Neutralize Hydrogen Peroxide
Magnesium
Hydrogen peroxide will naturally decompose into water and oxygen when exposed to sunlight, but it can also be rendered inert by adding oxalic acid, active carbon or many other mild acids. Hydrogen peroxide is more basic than acidic, so if it is necessary to neutralize it faster than it would automatically neutralize in sunlight, one must add some type of acid to bring its pH level value closer to 7.
..
Calcium
(Ca²+)
(NAC)
(ROS)
(SOCE)
ROS and SOCE: recent advances and controversies in the regulation of STIM and Orai
https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/jphysiol.2012.230565
Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(16)30147-5
..
PUFA
Polyunsaturated
Fatty Acid
Lipid Peroxidation
Hydroperoxyl
Hydrogen Peroxide
https://en.m.wikipedia.org/wiki/Hydroperoxyl
https://en.m.wikipedia.org/wiki/Polyunsaturated_fat
https://en.m.wikipedia.org/wiki/Lipid_peroxidation
..
Luminal Ca2+
Ferroptosis
Tetraspanin MS4A15
Synaptotagmin
C2 Domain
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling
https://www.nature.com/articles/s41418-021-00883-z
The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway
https://www.sciencedirect.com/science/article/abs/pii/S0969996108000284?via%3Dihub
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
https://www.nature.com/articles/s41418-020-0542-z
Alpha-synuclein fragments trigger distinct aggregation pathways
https://www.nature.com/articles/s41419-020-2285-7
..
everything from prion, seed oil, mycoplasma fermentans disrupting lipids.. everything is doing the same exact same thing, having to do with Iron, Calcium & mitochondria homeostasis.
Sarcalumenin (SAR) is an SR luminal glycoprotein responsible for Ca 2+ buffering
Impaired Ca2+ reuptake into the sarcoplasmic reticulum (SR) underlies a primary pathogenesis of heart failure in the aging heart
..
Aggregation of alpha-synuclein (αSyn) is a crucial event underlying the pathophysiology of synucleinopathies.
Synucleinopathies are a group of neurodegenerative diseases collectively characterized by intracellular protein inclusions containing alpha-synuclein (αSyn). αSyn is a predominantly presynaptic, intrinsically unfolded protein of 140 amino acids. Its primary structure comprises three distinct domains: (i) an N-terminal domain that binds lipids and adopts alpha helical structures, (ii) a central domain known as non-amyloid component (NAC) involved in aggregation, and (iii) a C-terminal acidic tail.
..
Dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease
"we found that higher Mg/Cu ratio resulted in significantly longer survival times after intracerebral CWD inoculation."
Magnesium in the Central Nervous System
Mg (Magnesium) levels were found to be decreased in various tissues of AD (Alzheimer’s Disease) patients and negatively correlated with clinical deterioration.
unfortunately Magnesium alone, un-buffered & un-chelated without Glycine, Nitrogen, Sulphur, ect.. is basically worthless.
..
Magnesium Status and Stress: The Vicious Circle Concept Revisited
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761127/
Magnesium deficiency and oxidative stress
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112180/
Magnesium Metabolism and its Disorders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855626/
Intracellular Mg2+ protects mitochondria from oxidative stress in human keratinocytes
https://www.nature.com/articles/s42003-023-05247-6
The Involvement of Mg2+ in Regulation of Cellular and Mitochondrial Functions
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516748/
Telomere Homeostasis: Interplay with Magnesium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796106/
Association of Dietary Magnesium Intake With Leukocyte Telomere Length
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161353/
Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications
https://www.mdpi.com/2073-4352/14/3/215
A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844918/
Mitochondrial Mg2+ homeostasis decides cellular energy metabolism and vulnerability to stress
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960558/
Functioning of potassium and magnesium in photosynthesis, photosynthate translocation and photoprotection
https://onlinelibrary.wiley.com/doi/full/10.1111/ppl.12747
Effects of Magnesium Oxide and Magnesium Hydroxide Microparticle Foliar Treatment on Tomato PR Gene Expression and Leaf Microbiome (insecticide)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228823/
Exogenous Calcium Reinforces Photosynthetic Pigment Content and Osmolyte, Enzymatic, and Non-Enzymatic Antioxidants Abundance and Alleviates Salt Stress in Bread Wheat
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097001/
Dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981212/
Effect of Mg2 +, Ca2 +, Sr2 + and Ba2 + metal ions on the antifungal activity of ZnO nanoparticles tested against Candida albicans
https://www.sciencedirect.com/science/article/pii/S092849311500212X
Magnesium Oxide-Catalyzed Conversion of Chitin to Lactic Acid
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/open.202000303
Why Thiamine Supplementation Requires Magnesium
https://hormonesmatter.com/why-thiamine-supplementation-requires-magnesium/
Functional Roles of Chelated Magnesium Ions in RNA Folding and Function
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747768/
Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
RE: o