Vitamin B1
Thiamine
Thiamin
Aneurin
Antiberiberi Factor
Thiaminium
Betaxin
Biamine

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Thiamine:

Nitrogen
Sulphur

Metalloenzyme:

Potassium
Magnesium

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Role of the Synthetic B1 Vitamin Sulbutiamine on Health

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210561/

Sulbutiamine is also a potent inhibitor of triosephosphate isomerase of the protozoan Encephalitozoon intestinalis causing microsporidosis, as shown by Garcia-Torres and colleagues. Sulbutiamine specifically inactivates the protozoan enzyme through interaction with cysteine residues, without affecting the human enzyme. This raises the possibility of using sulbutiamine in the treatment of microsporidosis.

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Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268695/

Thiamin
Pyrimidine
Thiazole
Methylene

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Enzyme
Alkaloid
Heterocycle
Cytochrome P450

Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants

https://www.frontiersin.org/articles/10.3389/fpls.2021.682181/full

Cytochrome P450: Polymorphisms and Roles in Cancer, Diabetes and Atherosclerosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171375/

https://en.m.wikipedia.org/wiki/Cytochrome_P450

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Thiamine (B1)
Quinine
Choline
Acetylcholine (ACH)
Acetylcysteine (NAC)

Thiamine and Quinine Differently Inhibit the Early Phase of

Acetylcholine-Dependent Contraction of Mouse Ileum in vitro

https://sciencepublishinggroup.com/article/10029853

The repertoire of human bitter taste receptors, TAS2R-1 were investigated to which thiamine and quinine may bind. These human bitter taste receptors were further analyzed among the database for mouse homologs using evolutionally conserved amino acid sequences. The only bitter receptor for both thiamine and quinine was TAS2R-39.

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Acetylcholine: How and Why to Optimize the Synthesis of this Vital Neurotransmitter

https://www.peirsoncenter.com/articles/acetylcholine-how-and-why-to-optimize-the-synthesis-of-this-vital-neurotransmitter

Thiamine as a peripheral neuro-protective agent in comparison with N-acetyl cysteine in axotomized rats

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329241/

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Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance

The non-coenzyme regulatory binding of thiamine compounds has been demonstrated for the transcriptional regulator p53, poly(ADP-ribose) polymerase, prion protein PRNP, and a number of key metabolic enzymes that do not use ThDP as a coenzyme.

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Bitter
Thiamine
Menthol
TRPM8
Icilin
WS-12

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was wondering why high dose of B1 was making me feel cold, and its bitter, tastes like enzyme supplements, and mybold injuries are being directly effected, old bone injuries feel colder, wondering if its healing?

the one article previously said a compound almost identical to B1 was able to bind, or cap off, the self assembling properties of prion from becoming amyloidogenic, im using B1 more like a medicine like Quinine, then just a therapeutic 100mg, im at 4000mg a day at the moment.