https://en.m.wikipedia.org/wiki/Importin

https://en.m.wikipedia.org/wiki/G_protein-coupled_receptor

Importin disease states and pathologies that are associated with mutations or changes in expression of importin-α and importin-β.

Importins are vital regulatory proteins during the processes of gametogenesis and embryogenesis. As a result, a disruption in the expression patterns of importin-α has been shown to cause fertility defects in Drosophila melanogaster (whitefly).