mycoplasma can completely mimic or copy the protein cell of the host cell. This can cause the immune system to begin attacking the body's own cells; an event that happens in all autoimmune diseases.

Some species of mycoplasmas also have the unique ability to completely evade the immune system. Once they attach to a host cell in the body, their unique plasma and protein coating can then mimic the cell wall of the host cell and the immune system cannot differentiate the mycoplasma from the body's own host cell.

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Endosymbiont are smaller then mycoplasma & also mimic host DNA.

antibiotics that are focused on bacteria shell are useless on endosymbiont, may be why mannose is more effective?