I remember my children's pediatrician told me sometimes to give them a double dose for the first dose and then schedule the remaining doses evenly. Have you every heard that suggestion?
This would depend on the drug. Perhaps there are drugs whose prescriptions can work as indicated. Unless the Ped is also a Pharmacist, I wouldn't take him seriously, though.
RE: Why 'Morning and Night' Isn't Always Good Enough for Your Medication.