he did not know.. although it was public knowledge.. Chris had NO idea.. it was clear from his reaction and what he said just after "that was a nice one!"

As well as the fact that he said he had no idea she had this disease.. Chris is a clever guy.. and a nice guy.. i believe him.. Chris has been doing stand up for ALONG TIME.. i think he wouldnt be dumb enough to make that joke if he knew in such a prominent situation.. ive seen a lot of his stand up work,, its not his style.. hes not nasty like some of the comedians