Not going to write a book on this subject. Infact I'm going to be cryptically succint. Do your own work....
Ripple
Dash
NXT
While I'm invested in many other coins, it is mostly for short term gains, or legacy payment systems that might gain & keep value simply for being first movers. That said, if I had to pick to hold my networth in something solid and trustworthy, my opinion has been expressed, as is.
What are your favourites? You don't need to say why...