Monkeypox manipulated in laboratory: two studies

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The Monkeypox has always been extremely rare and was first identified in humans in 1970 in the Democratic Republic of the Congo in a 9-year-old boy. Since then, human cases of monkeypox have been reported in 11 African countries. In 2003, the first monkeypox epidemic outside of Africa was recorded in the United States, and nothing like it has ever been recorded in multiple countries at the same time.

1 - A study published by the Portuguese Institute for Health found abnormal mutations in the presumed circulating monkeypox virus suggesting that it had been manipulated and modified into a biolab. The study found evidence that the virus responsible for the monkeypox epidemic that rages in Europe, America and Australia was heavily manipulated in a laboratory by scientists, and further evidence suggests that it was released intentionally.

NIH scientists collected clinical samples from 9 monkeypox patients between May 15 and May 17, 2022 and analyzed them.

Scientists have concluded that the monkeypox epidemic we are witnessing is most likely the result of a single origin because all the sequenced viruses released so far can cluster tightly together.

They also concluded that the virus belongs to the West African monkeypox virus clade. However, they found that it is most closely related to monkeypox viruses which were exported from Nigeria to several countries in 2018 and 2019, namely the UK, Israel and Singapore.

But while the virus looks a lot like those exported from Nigeria in 18/19, it is still very different with over 50 single nucleotide polymorphisms (SNPs), which are genetic mutations.

Based on normal evolutionary timelines, scientists would expect a virus like monkeypox to pick up many mutations in perhaps 50 years, not four. This is somewhat remarkable

2 - An other study from the European Molecular Biology Laboratory compared the evolution of 14 genomes of the monkeypox virus with the aim of discovering mutations or other viral evolutions (recombination) that could explain the sudden impact of this very low-level circulating epidemic.

What the scientists discovered is that the alleged circulating monkeypox virus contains a 30 T-long sequence at the center of the monkeypox genome, between the DNA-dependent RNA and the bovinepox inclusion protein of type A.

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According to scientists this never occurs completely within a sequence. Scientists argue that while that may be common in the termination of a genome, such as the termination of the monkey encephalitis virus, it is almost never completely encountered within a sequence.

So apparently we have a monkeypox virus circulating in different countries of the world at the same time for the first time in history, and this alleged virus has over 50 mutations that occurred in the space of 4 years instead of the 50 years it should have taken. And now we also know that it contains something that it just shouldn't be there.

References:

https://virological.org/t/multi-country-outbreak-of-monkeypox-virus-genetic-divergence-and-first-signs-of-microevolution/806

https://www.researchgate.net/publication/360973596_May_2022_Peculiar_Evolution_of_the_Monkeypox_Virus_Genomes

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Monkeypox manipulated in laboratory: two studies | Ecency