I've met so many smart people who struggle with their relationship with their spouse, with their parents, with their children and it's very obvious when it happens, most of them somehow assume that this was a side quest as opposed to the main quest of their career and financial achievements and they invested their time and energy accordingly and that was simply just not enough.
Some ambitions require better sacrifice but too many people seem to get confused throughout the journey and start forgetting that winning is no winning and if you destroy all your meaningful bonds with others in the process, when you choose the right timeline and scenario for your life it's not only at the top and this is quite the opposite that you might not even know or anything that ever exists in life.