I think perhaps you misunderstood what I was saying. Shadowrun is not like DnD. There are no alignments. Nobody is "good" or "evil". They just do things. Those things can be the result of a variety of motivations that the actor believes to be for the greater good.
Because the game sets up corps with so much power like private armies and extra-territorial powers, it's inevitable there will be conflicts or interest. Of course corps will sometimes do things that align with your own interests, but the most powerful motivator for any entity is self-interest. The primary self-interest for any corporation in the real world or in game is profit. Things that are most profitable rarely are good for the general public, so take away oversight and lots of shady stuff is likely to happen. Smart companies will try to do very good things publicly in order to keep up public perception, so it's up to us as GMs to use that tool to make the world more real, but I think like any other NPC or PC, corps need motivations for their actions and what most folks would consider "good deeds" rarely align with the primary motive of profit.
Most of the "evil stuff" corps do in my stories are a direct means to and end. Need to get that new product out faster? Maybe accelerate human trials. Maybe those participants are willing, maybe they are unaware. Or maybe the Corp giving you a job got some intel that another Corp was doing these trials and hires you to disrupt. It's up to us not to fall into simple good v evil tropes.
RE: Running The Sprawl: First impressions