By a News Reporter-Staff News Editor at Veterinary Week -- Investigators discuss new findings in Aromatic Polycyclic Hydrocarbons - Spiro Compounds. According to news reporting originating from Gifu, Japan, by VerticalNews correspondents, research stated, “To evaluate the safety of an intraoperative fluorescein sodium (FS) injection and elucidate the relationships between the MRI findings, pathological diagnoses, and intraoperative staining characteristics of intracranial lesions in 22 dogs. Prospective case series. Twenty-two dogs with intracranial lesions.”
Our news editors obtained a quote from the research from Gifu University, “FS was intravenously administered to 22 dogs undergoing craniotomy for suspected intracranial tumors to evaluate perioperative and postoperative adverse effects. The intensities and patterns of gadolinium (Gd) enhancement on preoperative magnetic resonance imaging and intraoperative FS staining were graded, and their relationship was evaluated. Intraoperative FS staining characteristics and pathological diagnoses were compared. The only adverse effect noted was repetitive vomiting in 2 dogs. The intensities and patterns between preoperative Gd enhancement and intraoperative FS staining appeared to agree. High-grade glioma and histiocytic sarcoma had more intense FS staining. Lesions with strong Gd enhancement, including meningiomas and choroid plexus tumors, also had intense FS staining. The intraoperative use of FS is a simple and safe technique to guide the resection of intracranial lesions in dogs. The findings on Gd enhancement, FS staining, and histopathology appeared to agree but require validation in a larger set of cases.”
According to the news editors, the research concluded: “The intraoperative use of FS may improve the prognosis of dogs with brain tumors by guiding the resection of lesions.”
For more information on this research see: Fluorescein sodium-guided resection of intracranial lesions in 22 dogs. Veterinary Surgery , 2017;():. Veterinary Surgery can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA. (Wiley-Blackwell - http://www.wiley.com/; Veterinary Surgery - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1532-950X)
The news editors report that additional information may be obtained by contacting Y. Nakano, The Animal Medical Center of Gifu University, Gifu University, Gifu, Japan. Additional authors for this research include K. Nakata, S. Shibata, Y. Heishima, H. Nishida, H. Sakai, H. Yano and H. Kamishina.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1111/vsu.12763. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
Publisher contact information for the journal Veterinary Surgery is: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA.
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CITATION: (2018-01-01), Findings on Spiro Compounds Reported by Researchers at Gifu University (Fluorescein sodium-guided resection of intracranial lesions in 22 dogs), Veterinary Week, 3, ISSN: 1944-2785, BUTTER® ID: 014920396
From the newsletter Veterinary Week.
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