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Everyones entitled to their opinion, to me the answer is easy. 2Pacs "Hit Em Up" Released June 4th 1996. He went after Biggie, Junior Mafia, lil kim and anyone else that ran their mouth. Chino xl to. Bold and aggressive I personally put it number one diss track of all time. I remade it about a week ago, on my youtube channel. Linked below. Thanks for taking the time to read and listen. Let me know your number one.