Amanita
The genus Amanita contains about 600 species of agarics including some of the most toxic known mushrooms found worldwide, as well as some well-regarded edible species. This genus is responsible for approximately 95% of the fatalities resulting from mushroom poisoning, with the death cap accounting for about 50% on its own. The most potent toxin present in these mushrooms is α-amanitin.
The genus also contains many edible mushrooms, but mycologists discourage mushroom hunters, other than knowledgeable experts, from selecting any of these for human consumption.