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There’s probably multiple facets to the reasons why this could be. The old school junkies dying off, people becoming smarter about prescription opioids due to all the news coverage, the bad stigma from marijuana slowly being revealed as false as its being decriminalized and regulated in various states, the availability and use of opioid blocking drugs like Narcan.
RE: Drug Overdose Deaths Drop in U.S. for First Time Since 1990