
thescientist
@thescientistPhD biochemist and science communicator
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RE: Connection of tau protein and Alheimer's disease. Does it help the body or provoke the illness?
The amyloid hypothesis has been the standard for 25 years, but I think it is just smoke, and the gun is yet to be discovered. Hyperphosphorylated TAU is cleaved by caspase-6 to generate a toxic fragment.