Well the 1 in 10^50 was not one guy rolling a die every second. That's one attempt per second per particle estimated to exist in the universe. 1 in 10^50 isn't even an estimate of the probability of a planet existing that is capable of supporting life. It's just a benchmark where even Mr. Spock would say "it's impossible." The probability of a planet existing that is capable of supporting life is 1 in 10^282. Source: https://reasons.org/explore/blogs/todays-new-reason-to-believe/read/tnrtb/2004/04/01/probability-for-life-on-earth

Every year, the probability goes down. As scientists discover new things that we never previously thought of. One small example, zinc is required for any sort of advanced life. But if you took the total amount of zinc on Earth and distributed evenly across the entire planet, Earth would be incapable of sustaining life.

We've gone from 1 in 10 planets supporting life (Drake, with no evidence) to 1 in 10^282. And every year I'm guessing that it will continue to go up. Even with billions and billions of stars with assuming billions of planets, we're looking at something so impossible that Earth should not have been able to have been created according to the laws of physics.