Many years ago I heard the mutant word in one of the early movies of the X-Men series. In addition to the X Man, Mutation is one of the many tools to create superheroes in many stories. However, the fact that we know about mutation in reality, most of the results are harmful. Now, if there is a harmful mutation between a person, he can live a healthy natural day, can he be called a superhero?
Only a few hundred people have been diagnosed with genes researching about 50,000 people who are healthy despite having a fatal mutation mutation. Of these fortunate 13, there are 8 types of genetic disorders mutation. 8 types of disorders including cystic fibrosis, osteocytosis, in which children with infertility do not live longer than birth.
Eric Shut of Icon School of Medicine and Stefan Friend of Sage Beyonetworks, a non-profit organization, led the study. The famous biotechnology company 23andme and the Beijing Genomics Institute initially provided DNA sequence of 589,306 people. Of these, 3,524 people had complete GNOME sequence. The rest were mutual testing information for XM sequences or certain genes.
Dr. Eric, Dr. Friend and their colleagues only reduce the sequence number 15,597, considering the presence of mutations associated with Mendelian disorder. Although there are different mutations in those genes, those mutations that always cause disease are selected. These 15,597 people have at least one of the mutations associated with 163 disorders.
At this stage, they have omitted those sequences that may have been wrong. Afterwards, those mutations which are found in 0.5 percent of the population are excluded. Because of the kind of mutation usually the intensity of the disease is mild. In this situation, only 303 people who have a medical report say they are carrying out the mutations that are completely healthy and scientifically proven deadly in all genetic diseases, as people die before maturity. Researchers have recovered biological samples and tested DNA sequences for those cases they have done.
In the end, only 13 people took a lot of verification. But the problem is that each of these sequences is a partial sequence. Then, the next logical step could be to see their entire DNA sequence. For what reason these devastating mutations, which are the cause of death of common people, they are still in force. If any gene is found, which is creating a possible defense system, then cut it and insert it into the cells of the laboratory and observe ... what results are available. Or it may be that some other mutation of their genome protects them. Again, it may also be that any elements of the environment they live in may be preventing them from being infected. Which can be a lot of things
If properly known, it may be possible to invent a new type of medical treatment for those diseases. It is a disappointment that researchers can not do this. Because the Subjects, whose DNA research was done, did not specify their address or contact form in the agreement. So far the identity of these genetic superheroes is a mystery. Maybe they are roaming around us, we can not recognize them, they also do not know about their power.
