Thanks for sharing this information. Like what @abigail-dantes said I got an impression that once a metastatic neoplasm in the brain is detected there is hardly any hope for the patient. I am also guessing that by the time it is symptomatic it might already be in later stages like in most metastatic diseases. Are there any success stories too around curing the condition? Also, a bit hyperbolic question for this is more related to my field would be - are there any current immunotherapy options for metastatic brain tumors? What are the major limitations for such therapies, if any?