T memory cell

The generation of T memory cells is always a mystery. The antigen spacefic nature of T-Cell
clearly implies that T cells possess an antigen-
specific and clonally restricted receptor. However, the identity of this receptor remained unknown long after the B-cell receptor (immunoglobulin molecule) had been
identified. Important new insights concerning T-cell receptors have been gained by recent structure determinations using x-ray crystallography, including new awareness of differences in how TCRs bind to class I or class II MHC molecules.