Alström syndrome (AS), also called Alström–Hallgren syndrome,[1] is a rare genetic disorder caused by mutations in the gene ALMS1. It is among the rarest genetic disorders in the world, as currently it has only 266 reported cases in medical literature and over 501 known cases in 47 countries. It was first described by Carl-Henry Alström and his three associates B. Hallgren, I. B. Nilsson and H. Asander in Sweden in 1959.[2] Alstrom syndrome is sometimes confused with Bardet–Biedl syndrome, which has similar symptoms. Bardet-Biedl syndrome tends to have later onset in its symptoms
