Pox is a group of rare autoimmune diseases characterized by scattering that affects the skin and mucous membranes. [1]
In the pox, antibodies are formed against dsmoglen. Dismoglen is the adhesive that binds skin cells to points called dizzosomes. So when self-antibodies target dsmoglen, the skin cells become non-aligned and the so-called thrombosis occurs. This causes scattering and leads to ulceration. This scattering may cover clear areas of the skin. [2]
Originally, the cause of the bubonic plague is unknown. The label was used to describe any skin and mucosal scattering disease. But in 1964, researchers found that the patients' blood contained antibodies in the layers of the affected skin. [3] [4] In 1971, an article was published on the detection of antibodies in this disease
