They are not placebos. The remedies can effect astonishing improvment in all types of disease.

Not all undesirable mental states can be fixed by positive thinking. Very often disease also affects the mind. The mind is not separate from the body. For instance, hypothyoidism causes extreme fatigue which in turn can cause depression. We would treat the hypothyroidism foremost, and possibly add a remedy for more immediate relief of the concomitant depression.