Previously in the First World War, a soldier who was hit by a bullet in one of his limbs faced the harsh reality of an amputation? Doctors in ancient wars did not have any type of medicine that would treat open wounds prone to an infection that in a few days or hours claimed the lives of many people, so to avoid an infection the best cure was amputation! But in 1928 a man who revolutionized the field of medicine and unknowingly created an antibiotic capable of saving the lives of thousands of people!😮😲
Anteriormente en la primera guerra mundial un soldado que era alcanzado por una bala en uno de sus miembros enfrentaba la cruda realidad de una amputacion! los medicos en las guerras antiguas no tenian ningun tipo de medicamente que tratara heridas abiertas propensas a sufrir una infeccion que en pocos dias o horas cobraban la vida de muchas personas, asi que para evitar una infeccion la mejor cura era la amputacion! pero en 1928 un hombre revolucionaria el campo de la medicina y sin saberlo crearia un antibiotico capaz de salvar la vida de miles de personas!👨🔬👨⚕️🧬
THE GREAT FLEMING👨🏫👴/EL GRAN FLEMING🔬🧫
I do not think that Alexander Fleming was aware of his great discovery, and it is that this revolutionary British character in the field of medicine and pharmacology, it all happened in 1928 Fleming was at that time a professor at a London university, and he was the first to discover a true, authentic and functional antibiotic! Alexander took bacterial colonies, sorted them into petri dishes! These bacteria were harmful to our health and caused some minor illnesses. One day Fleming noticed that there were bacteria all over the capsule except where the mold was growing!😮🤔
No creo que Alexander Fleming estaba consciente de su gran descubrimiento, y es que este personaje britanico revolucionaria el campo de la medicina y farmacologia, todo ocurrio en 1928 Fleming era en esa epoca profesor de una universidad de Londres, y fue el primero en descubrir una verdadero, autentico y funcional antibiotico! Alexander tomaba colonias bacterianas, las clasificaba en capsulas de petri! estas bacterias eran perjudiciales para nuestra salud causaban algunas enfermedades leves, un dia Fleming noto que habian bacterias por toda la capsula a exepcion de donde estaba creciendo el moho! 🔬💊🧫
Fleming would not stay there classified that fungus which belonged to the genus Penicillium, the species was (Penicillium notatum), the professor immediately perceived that the fungus had secreted some chemical compound that inhibited bacterial growth in its surroundings! This is a mechanism of adaptation and evolution of fungi to basically "kill" their competition and spread by itself, days later Alexandre created a liquid that had been extracted from the secretion of P. notatum, and was shocked with its results since its "magic liquid" killed a large number of bacteria that were harmful to humans!🧠👨🏫
Fleming no se quedaria alli clasifico ese hongo el cual pertenecia el genero Penicillium, la especie era (Penicillium notatum), el profesor percibio inmediatamente que el hongo habia secretado algun compuesto quimico que inhibia el crecimiento bacteriano a sus alrededores! esto es un mecanismo de adaptacion y evolucion de los hongos para basicamente "matar" su competencia y propagarse el solo, dias despues Alexandre creo un liquido al que habia sido extraido de la secrecion de P. notatum, y quedo impactado con sus resultados ya que su "liquido magico" mataba una gran cantidad de bacterias que eran dañidas para el ser humano! 🧬👨🔬
PENICILLIN ISOLATION👨🏫👴/AISLAMIENTO DE LA PENICILINA🔬🧫
Well, Fleming had done the most difficult part, which was to discover an antibiotic, but a "liquid" extracted from the fungus cannot be used, it was necessary to extract the penicillin from the liquid, that is, the PURE compound, so he entrusted this difficult task to his two assistants but they did not count. With an obstacle that the compound was unstable and difficult to isolate, of course it was time for Fleming to publish his discovery and that he did in a scientific journal in 1929, many scientists saw the results of his research and tried to isolate penicillin but one after another failed. ! it seemed like an impossible job!😲👨⚕️
Bien Fleming habia hecho la parte mas dificil que era descubrir un antibiotico pero no se puede usar un "liquido" extraido del hongo, se necesitaba extraer la penicilina del liquido osea el compuesto PURO, entonces encomendo esta dificil tarea a sus dos asistentes pero no contaban con un obstaculo que el compuesto era inestable y dificil de aislar, claro era momento de que Fleming publicara su descubrimiento y eso hizo en una revista cientifica en 1929, muchos cientificos vieron los resultados de su investigacion e intentaron aislar la penicilina pero uno tras otro fracaso! parecia un trabajo imposible!🧫🧫
In 1939, the Second World War was in progress and it made it difficult to investigate Fleming's curious work, but his assistants never stopped to give us an idea of how difficult the work of synthesizing penicillin was. Florey and Chain processed more than 500 liters per week. of the liquid secreted by the fungus, only a year had passed and in 1940 Florey discovered by experimenting with mice that penicillin protected them from pathogens, it seems that the work was coming to an end and in 1941 penicillin was first experimented in the human being! the subject who would try penicillin for the first time had an infection!🐁🐁
En 1939 estaba en transcurso la segunda guerra mundial y dificulto la investigacion del curioso trabajo de Fleming, pero sus asistentes nunca se detuvieron para que tengamos una idea de lo dificil que era el trabajo de sintetizar la penicilina Florey y Chain procesaban mas de 500litros por semana del liquido que secretaba el hongo, habia pasado tan solo un año y en 1940 Florey descubrio experimentando con ratones que la penicilina los protegia de patogenos, parece que el trabajo estaba llegando a su punto final y en 1941 se experimenta por primera vez la penicilina en el ser humano! el sujeto el cual probaria la penicilina por primera vez tenia una infeccion!👨🦱👨
The man who was infected was in very poor health, so he was injected with penicillin and after a few days he began to recover, but Fleming's assistants had run out of supply and he could not inject the man with another dose and he ended up dying. ! but everything pointed out that the medicine was ready and that there were no side effects in people! Do you know what happened next? penicillin began to be mass produced in order to be released in the second world war. It would be the end of unnecessary amputations for lack of an antibiotic!🕵️♀️🕵️♂️
El hombre que estaba infectado se encontraba en muy mal estado de salud, entonces se le inyecto la penicilina y pasado unos dias comenzo a recuperarse, pero los asistentes de Fleming se habian quedado sin suministro y no pudo inyectarsele al hombre otra dosis y acabo por morir! pero todo apuntaba que ya estaba listo el medicamento y que no habian ningun efecto secundario en las personas! saben que paso despues?? la penicilina comenzo a producirse en masa con el fin de ser estrenada en la segunda guerra mundial. Seria el fin de las amputaciones innecesarias por falta de un antibiotico!🤔😮😇
A country that suffered the constant Nazi bombings made it impossible to produce the drug en masse was by no means easy, since the most difficult work had been done by Fleming and his assistants! now it was the job of the industries to mass produce the antibiotic to save the lives of many allied soldiers, sadly only began to industrialize on a large scale penicillin at the end of 1943 almost two billion of the drug was produced. After the second war ended in 1945, penicillin began to invade pharmacies around the world, saving thousands of lives!😮😮
No era nada facil un pais que sufria los constantes bombardeos nazis imposibilitavan la produccion del medicamento en masa, ya el trabajo mas dificil lo habia echo Fleming y sus asistentes! ahora era trabajo de las industrias producir en masa el antibiotico para salvar la vida de muchos soldados aliados, tristemente solo se comenzo a industrializar en gran escala la penicilina a finales de 1943 casi dos billones del medicamente se producian. Luego que la segunda guerra termina en 1945 la penicilina comienza a invadir las farmacias de todo el mundo salvando miles de vida!😍😍
CHARACTERISTICS OF THE GENRE PENICILLIUM👨🏫👴/CARACTERÍSTICAS DEL GÉNERO PENICILLIUM🔬🧫
It is time to leave the history of penicillin and let's focus on the main characteristics of this genre! They are micro-fungi, of which it is known that there are more than 300 species, and there are still many more to be discovered, many species are used in the fields of pharmacology, medicine and food! but only one species was immortalized and it is (Penicillium chrysogenum) because of it the famous antibiotic was produced!😮😮
Es hora de dejar la historia de la penicilina y vamos a enfocarnos en las principales caracteristicas de este genero! son microhongos, de los que se sabe que existen mas de 300 especies, y aun existen muchas mas por descubrir, muchas especies son usadas en el campo de la farmacologia, medicina y alimento! pero solo una especie se inmortalizo y es (Penicillium chrysogenum) porque de ella se produjo el famoso antibiotico!🧫🍄
When we mention the word penicillium, the first character that comes to mind is Fleming, but actually in the 18th century some species of fungi of this genus had already been discovered, I always wondered how almost all foods can be infected by this fungus? and it is that its propagation is by bone spores, small structures fly throughout the environment and colonize the soil, food! When we seal our food without oxygen, although we can capture some spores, they do not grow due to lack of oxygen!😲🍄🧫
Cuando mencionamos la palabra penicillium el primer personaje que nos viene a mente es Fleming pero en realidad en el siglo 18 ya se habian descubierto algunas especies de hongos de este genero, siempre me preguntaba como es que casi todos los alimentos pueden infectarse por este hongo? y es que su propagacion es por esporas osea pequeñas estructuras vuelan por todo el ambiente y van colonizando el suelo, alimento! cuando sellamos nuestro alimento sin oxigeno apesar de que podemos capturar algunas esporas no crecen por falta de oxigeno!🤔👨🏫🧬
OTHER DATA👨🏫👴/OTROS DATOS🔬🧫
Many species of the genus Penicillium are not toxic for us but others can produce some toxins that can cause some allergies, foods such as some cheeses are produced by a chemical reaction of some fungi towards milk, but it is not toxic and safe to eat! therefore micro-fungi of this genus have facilitated the production of many foods!😲🍴🧀🧀
Muchas especies del genero Penicillium no son toxicas para nosotros pero otras pueden producir algunas toxinas que pueden causarnos algunas alergias, alimentos como algunos quesos son producidos por una reaccion quimica de algunos hongos hacia la leche, pero no es toxico y seguro de comer! por tanto los microhongos de este genero han facilitado la produccion de muchos alimentos!🧫🕵️♂️👨🔬🧠
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The following post corresponds to a compilation of information extracted from the following pages:📕📕 / The scientific experience and photos are my property🤗
https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/historia-quimica/descubrimiento-desarrollo-penicilina.html
https://es.wikipedia.org/wiki/Penicillium