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Fibromyalgia is the second most frequent disease that affects your bones and muscles. It is a chronic disorder that causes pain (musculoskeletal pain) and tenderness throughout the body. Also, it can make you feel fatigued, which results in mental side effects, including memory loss. Fibromyalgia is more common in women than in men. Several patients with fibromyalgia also experience tension headaches, irritable bowel syndrome, temporomandibular joint (TMJ) disorders, anxiety, and depression.