Adult Stem Cell Regeneration
Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells
https://pmc.ncbi.nlm.nih.gov/articles/PMC6294242/
Adult Stem Cell Regeneration:
Adult stem cells are involved in tissue repair and regeneration throughout life. Niacin's ability to boost NAD+ and improve mitochondrial function may contribute to the rejuvenation and enhanced activity of these stem cells.
Research also suggests that niacin can enhance the expansion of adult stem cells from various tissues, including pancreas, colon, bone marrow, and umbilical cord.
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy
Royal Jelly
Honey
Amono Acid
Methionine
Hematopoietic
Stem Cell
Regeneration
Royal jelly, a substance secreted by honeybees, contains methionine and other amino acids, and has shown potential in promoting stem cell function and regenerative processes, with some studies suggesting its ability to increase hematopoietic stem cell counts and enhance learning and memory.
New Insights into the Biological and Pharmaceutical Properties of Royal Jelly
https://pmc.ncbi.nlm.nih.gov/articles/PMC7014095/
Royal Jelly: Biological Action and Health Benefits
https://pmc.ncbi.nlm.nih.gov/articles/PMC11172503/
Royal Jelly Increases Hematopoietic Stem Cells in Peripheral Blood
https://pmc.ncbi.nlm.nih.gov/articles/PMC9859695/
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Hydroxycarboxylic Acid
Receptor 2
GPR109A
HCA2
GPER
AREG
Ribose
Nicotinamide Riboside
Prostaglandin
Short-Chain Fatty Acid (SCFA)
Dietary Fiber Fermentation
https://en.m.wikipedia.org/wiki/Hydroxycarboxylic_acid_receptor_2
https://en.m.wikipedia.org/wiki/GPER
Niacin
Insulin
Sensitivity
Resistance
Sirtuin
Adiponectin
T2D
Sulfur Insulin
Deformation Hypothesis
Niacin (Vitamin B3)
Niacin fine-tunes energy homeostasis through canonical GPR109A signaling
https://www.biorxiv.org/content/10.1101/382416v1.full
Niacin regulates glucose metabolism and osteogenic differentiation via the SIRT2-C/EBPβ-AREG signaling axis
https://www.sciencedirect.com/science/article/pii/S0753332224013337
The Promise of Niacin in Neurology
https://www.sciencedirect.com/science/article/pii/S1878747923019104
Unraveling the Sulfur Insulin Deformation Hypothesis: A Novel Therapeutic Avenue for Type 2 Diabetes
https://www.qeios.com/read/UK9O6V
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Hypothalamus
Brain Waves
Alpha Theta
Alpha waves (8-12 Hz): Associated with relaxed wakefulness, meditation, and daydreaming.
Theta waves (4-8 Hz): Linked to deep relaxation, meditation, dreaming, and daydreaming.
The hypothalamus is a key brain region involved in regulating homeostasis, including body temperature, hunger, thirst, and sleep-wake cycles.
The hypothalamus's role in regulating sleep-wake cycles can influence the dominance of different brainwave frequencies (e.g., theta waves during sleep, beta waves during wakefulness).
The hypothalamus can also influence brainwave activity through its connections with other brain regions, such as the limbic system and cortex.
Theta waves are particularly prominent in the hippocampus, a brain region crucial for memory formation and spatial navigation.
Theta oscillations in the hippocampus are thought to play a role in coordinating neuronal activity and facilitating memory consolidation.
RE: Intercellular Homeostasis