Glycine
Sarcosine
N-Methylglycine
Monomethylglycine
Methylamino-Acetic Acid
Unexplored Excipients in Biotherapeutic Formulations: Natural Osmolytes as Potential Stabilizers Against Thermally Induced Aggregation of IgG1 Biotherapeutics
https://link.springer.com/article/10.1208/s12249-021-02183-8
results rank the osmolytes’ stabilizing trend to be sarcosine > betaine > hydroxyectoine > ectoine. Sarcosine emerged as the most successful osmolyte rendering highest degree of protection against aggregation.
The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727032/
..
Glycerol
Glycine
Sarcosine
Betaine
Proline
Choline
Taurine
Sorbitol
Inositol
RE: o