Pomegranate
Tannin
Copper
Urolithin A
Postbiotic
a polyphenol from pomegranate that must be fermented to become Urolithin.
Tannin complexation with metal ions and its implication on human health, environment and industry
https://www.sciencedirect.com/science/article/abs/pii/S0141813023043829
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Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes
https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-020-00976-5
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https://en.m.wikipedia.org/wiki/Acrydite
https://en.m.wikipedia.org/wiki/Acrylamide
https://en.m.wikipedia.org/wiki/Demethylation
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my point is the DNA can be stunted by starvation, the Cromagnon look like European people of larger size, Neanderthal look Arabic in larger size.
DNA Methylation via starvation has the ability to stunt growth.
something bizarre happened in human civilization past, megalithic structures, using an unknown technology & larger size.
afterwards, we are smaller & riddled with chromosome disease.
and the history blames Ganges Khan & Justinian Plague.
i think we are the Atlantis people, just widdled down smaller, via DNA Methylation via some kind of ancient Protist biowarfare.
making our powerful DNA into junk DNA.
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Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030913/
Neutralizing Mutations Significantly Inhibit Amyloid Formation by Human Prion Protein and Decrease Its Cytotoxicity
https://www.sciencedirect.com/science/article/abs/pii/S0022283619306977?via%3Dihub
G127V & G127I
this was the basic idea for the vinegar/mineral ions, to make monoatomic zwitterionic ions, that would cap off every unbound radical with the oppsite ions, effectively neutralizing prion, viruses & bind up parasites like fermentation chemicals ivermectin.
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An ancient metalloenzyme evolves through metal preference modulation
https://www.nature.com/articles/s41559-023-02012-0
consist mostly of eukaryotic mitochondrial SodFMs (for example, human mitochondrial Mn-SOD) and a few bacterial sequences including that of Parachlamydia acanthamoebae (Fig. 2a). Grouping of the highly distinct mitochondrial SODs with sequences from Chlamydia could represent functional convergence, eukaryote to prokaryote lateral gene transfer (LGT) or be evidence of ancient LGT between the bacterial ancestor of mitochondria and that of Chlamydia.
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Genome Engineering of the Fast-Growing Mycoplasma feriruminatoris toward a Live Vaccine Chassis
https://pubs.acs.org/doi/10.1021/acssynbio.2c00062
except its not a real yeast.. but likely a GMO "Yeast-Like" Protist mitDNA.
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Sickle Cell Malaria Hypothesis
Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis
https://www.nature.com/articles/ncomms1104
The evolutionary link between sickle-cell trait and malaria resistance showed that humans can and do adapt. But are the “bugs” that make us sick evolving as well?
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Mitochondria DNA Parasite
Amoebophyra
Multinucleate
Syndiniale
A marine parasite’s mitochondria lack DNA but still churn out energy
https://www.sciencenews.org/article/marine-parasite-mitochondria-no-dna-energy
https://en.m.wikipedia.org/wiki/Amoebophyra
https://en.m.wikipedia.org/wiki/Syndiniales
https://en.m.wikipedia.org/wiki/Multinucleate
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Protist Plastid
Endosymbiont
Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae
https://www.nature.com/articles/s41467-021-26918-0
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Metallome
Metalloenzyme
PH
Ion
Mitochondria
Redox
Amyloid
Redox-Active Metal Ions and Amyloid-Degrading Enzymes in Alzheimer’s Disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307724/
pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828734/
Imidazole
Zwitterion
https://en.m.wikipedia.org/wiki/Imidazole
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Zwitterions as building blocks for functional liquid crystals and block copolymers
https://www.nature.com/articles/pj20176
Design and properties of functional zwitterions derived from ionic liquids
https://pubs.rsc.org/en/content/articlelanding/2018/cp/c7cp08592c
The word “zwitterion” means an ion pair where the cation and anion are covalently tethered.
amino acids are typical ZIs at moderate pH in an aqueous medium.
Functional zwitterions (ZIs)
Ionic liquids (ILs)
Covalently Tethered
Neutral PH
Hydrolysis
Ion Cation Cnion
Hydrolysis
Covalent Bond
PH:
Potential of Hydrogen
Power of Hydrogen
Acid–base equilibria:
acid dissociation constant, hydrolysis, buffer solutions, indicators, acid–base homeostasis
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A zwitterionic solution for smart ionic liquids to evade cytotoxicity
https://www.sciencedirect.com/science/article/abs/pii/S0304389423007136?via%3Dihub
Structural analysis of zwitterionic liquids vs. homologous ionic liquids
Mixed-charge pseudo-zwitterionic copolymer brush as broad spectrum antibiofilm coating
https://www.sciencedirect.com/science/article/abs/pii/S0142961221001502
Unexpected Function of a Heptapeptide-Conjugated Zwitterionic Polymer that Coassembles into β-Amyloid Fibrils and Eliminates the Amyloid Cytotoxicity
https://pubs.acs.org/doi/10.1021/acsami.1c01132
Zwitterionic polymers-armored amyloid-like protein surface combats thrombosis and biofouling
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556425/
Inhibition of protein aggregation by zwitterionic polymer-based core-shell nanogels
RE: Protonation Cation/Anion