@mikewick77: Nitrification

Nitrification has traditionally thought to be a two-step process, where ammonia-oxidizing bacteria and archaea oxidize ammonia to nitrite and then nitrite-oxidizing bacteria convert to nitrate.

how Archaea affects: Lipid, Phosphorus, Nitrogen & Iron.. of blood.

Ammonia-oxidising organisms disrupt Nitrogen, by disrupting the Phospholipid?

Ammonia-oxidizing archaea possess a wide range of cellular ammonia affinities.

it seems to be doing the opposite of what i said..

"ammonia-oxidising organisms disrupt Nitrogen, by disrupting the Phospholipid."

the reverse.. disrupting the Nitrogen affects the Phospholipid.

or did i make that the same way twice?

if we can pinpoint what domino is first, then is a good clue.

this would be why Nicotine & Niacin are so helpful, because of the Nitrogen.

the good kind of Nitrogen, apposed to Nitrate in freezer foods.. like Antifreeze?

Liquid Nitrogen
Ammonia
Antifreeze

the Nitrate maybe forming Phospholipid problems?

how to convert bad Nitrate into good Nitric Oxide? what is the mechanism? or is Nitrate to bound or calcifie?

How do nitrated lipids affect the properties of phospholipid membranes?

https://www.sciencedirect.com/science/article/pii/S0003986120305579?via%3Dihub

Nitro-Oxidized Lipids

https://en.m.wikipedia.org/wiki/Aldehyde

https://en.m.wikipedia.org/wiki/Heme_oxygenase

Oxidized phospholipids in excess in the circulation are considered to be biomarkers of atherosclerosis, and oxidized phosphatidylcholine bound to lipoproteins containing apoB-100 is reported to be a biomarker for calcific aortic valve stenosis, stroke and coronary events.

Biological membranes are under constant attack of free radicals, which may lead to lipid nitro-oxidation, producing a complex mixture of nitro-oxidized lipids that are responsible for structural and dynamic changes on the membrane. Despite the latter, nitro-oxidized lipids are also associated with several inflammatory and neurodegenerative diseases, the underlying mechanisms of which remain elusive.

Nitric oxide (NO) is a free radical with an unpaired electron in the highest orbital. This is why it behaves as a potential antioxidant agent by virtue of its ability to reduce other molecules. In vitro experiments support this concept inasmuch as NO is able to inhibit lipid peroxidation.

nitrogen dioxide will both oxidize and nitrate unsaturated lipids, with nitration occurring by hydrogen abstraction and addition reactions. These reactions result in formation of a complex mixture of products including nitrated lipid derivatives and alkylnitrites.

its stealing the Nitrogen, converting Nitro-Oxidized Lipids into Oxidized Phospholipid?

Nitro-Oxidized
Phospholipid Oxide

its both bad..

but does the Nitro trigger the Phos?

is why Nician is helpful, breaks up plack by swapping with calcifie atoms, breaking it up, similar to citric acid breaks up kidney stones.

so Nitrogen is the master element for Lipids, going good or bad.

how to convert bad Nitrogen into good? not just add more Nitrogen, making lipid use good Nitrogen, but also unbind nitrates from misfolding protein.

Phosphate is one of the most abundant elements in protein, if it goes the wrong direction, is bad problems.

we are full of Phosphorus.

but something is folding it wrong, via Nitrate.

inorganic phosphate

Inorganic phosphorus (phosphate ester) is one of the major constituents of bones.

somehow a microbe is disrupting endothelium lipid via nitrate into toxic phospholipid protein misfolding.

wonder what medications use archaea fermentation or as crisper?

i think Archaea make Exosomes similar enough to animals to be a candidate for virus horizontal data transfer.

if Archaebiotics can be used for good results, can also the reverse.

methanomassiliicoccus-luminyensis-la-plus-grosse-archae-humaine-2.6mb_img.jpg

the only pictures of this Archaea on the internet, and the website not available, only the picture.

Archaea is a
Alphaproteobacteria?

Methanomassiliicoccus

https://species.m.wikimedia.org/wiki/Methanomassiliicoccus

And as Methanomassiliicoccus sits in the gut it can restrict the gut's natural abilty to fight infection by the production of methane

Another form of cross-species manipulation as Scientists often use Alphaproteobacteria of the genus Agrobacterium to transfer foreign DNA into plant genomes

does Methane Oxide Nitrogen?

Methane and Nitrogen oxide are being spewed as Methane and nitrous oxide are important greenhouse gases. They contribute to global warming. To a large extent, emissions of methane and nitrous oxide are connected with the intensification of food production. But most of this would point more towards the chemical fertilization of plants and cow farts

Methanol and ethylene glycol poisoning:

https://www.uptodate.com/contents/methanol-and-ethylene-glycol-poisoning-management#!

Ethylene-Oxide
Antifreeze

Ethylene
Methanol

its making antifreeze derivatives to compromise the immune system.

Methanogenic Archaea and oral infections — ways to unravel the black box

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086593/

Evidence that the human immune system recognizes and responds to Archaea comes from older studies that investigated the potential of archaeal cell membrane lipids (incorporated into liposomes and generally referred to as ‘archaeosomes’) as self-adjuvanting antigen-delivery vehicles.

methanogenic
methanogens
methylated
Methanobrevibacter Oralis
Interspecies Hydrogen Transfer

Archaeosome
Liposomes

Archaeosomes: an excellent carrier for drug and cell delivery

https://www.tandfonline.com/doi/full/10.3109/10717544.2015.1019653

Archaeosomes are widely used as drug delivery systems for cancer vaccines, Chagas disease, proteins and peptides, gene delivery, antigen delivery.

Archaeal lipids play an important role from the production of pharmaceutical product to their stability maintainer.

The archaeal lipids are more stable than other phospholipids.

SASP
Senescence Associated Secretory Phenotype

https://en.m.wikipedia.org/wiki/Senescence-associated_secretory_phenotype

(SASP) is a phenotype associated with senescent cells wherein those cells secrete high levels of inflammatory cytokines, immune modulators, growth factors, and proteases.

SASP may also consist of exosomes and ectosomes containing enzymes, microRNA, DNA fragments, chemokines, and other bioactive factors.

SASP is the primary cause of the detrimental effects of senescent cells.

Chronic inflammation due to SASP can suppress immune system function, which is one reason elderly persons are more vulnerable to COVID-19.

Transforming growth factor beta family members secreted by senescent cells impede differentiation of adipocytes, leading to insulin resistance.

SASP from senescent cells is associated with many aging-associated diseases, including not only cancer, but atherosclerosis and osteoarthritis. For this reason, senolytic therapy has been proposed as a generalized treatment for these and many other diseases.

The flavonoid apigenin has been show to strongly inhibit SASP production.

@mikewick77: Nitrification | Ecency