RE: RE: Disease-X
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RE: Disease-X

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Direct Nanopore Sequencing of mRNA Reveals Landscape of Transcript Isoforms in Apicomplexan Parasites.

https://www.meta.org/papers/direct-nanopore-sequencing-of-mrna-reveals/33688018

Sensing Host Arginine Is Essential for Leishmania Parasites' Intracellular Development

https://pubmed.ncbi.nlm.nih.gov/33051367/

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it appears to be undigestable to microbes, i suspect it binds to all pathogenic microbes digestion & internally binds them up. them, similar to lactose Intolerance, allowingvthe immune system to identify them.

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https://pubmed.ncbi.nlm.nih.gov/34663707/

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8081047/

Objectives: To investigate the association between mannose-binding lectin 2 (MBL2) codon 54 polymorphism and clinical features of patients diagnosed with schizophrenia (SCZ) or bipolar disorder (BD).

GluA2 subunits isolated from individuals with schizophrenia showed significantly lower levels of high-mannose/hybrid glycans revealed by EndoH treatment as well as decreased binding to ConA, a lectin that binds high mannose and complex N-glycans.

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High-Mannose But Not Complex-Type Glycosylation of Tetherin Is Required for Restriction of HIV-1 Release

https://pubmed.ncbi.nlm.nih.gov/29303997/

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5Glycosylation Precursors

https://www.ncbi.nlm.nih.gov/books/NBK453043/

A Novel Functional Role of Collagen Glycosylation

INTERACTION WITH THE ENDOCYTIC COLLAGEN RECEPTOR uPARAP/ENDO180*

https://www.jbc.org/article/S0021-9258(20)50982-4/fulltext

Collagen glycosylation

https://www.physiol.uzh.ch/en/Glycosylation/Oglycosylations/Collagenglycosylation.html

glycosylated Hyl also occurs in the collagen domains of non-fibrillar soluble proteins such as members of the collectin family encompassing the complement protein C1q, the mannose-binding lectin MBL and the surfactant proteins A and D. Since the collagen domain of collectins is involved in the oligomerization process, it is likely that the glycan chains participate in this process.

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Glycosylation
Mannose-Binding Lectin MBL

Mannose binding lectin (MBL) and HIV

https://pubmed.ncbi.nlm.nih.gov/15488604/

Potential site of attack by the innate immune system through the C-type lectin mannose binding lectin (MBL) (also called mannan binding lectin or mannan binding protein). A number of studies have clearly shown that MBL binds to HIV.

@mikewick77: Direct Nanopore | Ecency