Chrétien & Mbikay
Quercetin
PCSK9 Inhibitor
https://www.mcgilltribune.com/sci-tech/montreal-researchers-propose-a-treatment-for-covid-19-170320/
"A cell has a lock, and the virus has a key [to enter and infect the cell], But quercetin puts glue in the lock"
“[Quercetin] costs peanuts compared to the antivirals that are on the market, which cost sometimes $1000 [per] shot,” Chrétien said. “Two months ago, you could have a one day treatment [of over-the-counter quercetin] for two dollars.”
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https://www.medicalnewstoday.com/articles/323037#health-benefits
https://www.student-baba.com/2019/07/vitamins-produced-by-microbial.html?m=1
Bioconversion of Kaempferol and Quercetin Glucoside
https://www.mdpi.com/2311-5637/4/4/102/htm
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https://en.m.wikipedia.org/wiki/Ionophore
https://en.m.wikipedia.org/wiki/Flavonols
https://en.m.wikipedia.org/wiki/Aglycone
https://en.m.wikipedia.org/wiki/Glucoside
https://en.m.wikipedia.org/wiki/Acylation
https://en.m.wikipedia.org/wiki/Ester
https://en.m.wikipedia.org/wiki/Lipid
https://en.m.wikipedia.org/wiki/Rutin
https://en.m.wikipedia.org/wiki/Kaempferol
Bioconversion of Kaempferol and Quercetin Glucoside
Glucoside
Aglycone
Acylation
Ester
Lipid
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going threw the process, bacteria & yeast both alter the process in so many ways, its almost impossible to clearly understand what is going on.
i dont trust plant, vitamin or medical sources, specifically if the supply chain is broken, we need the manufacturing process.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928927/
flavonols and flavones in tea are mainly found as glycosides, and their types and compositions vary with tea type and cultivar [2,3]. Aglycones of flavonols such as kaempferol, myricetin, and quercetin as well as their glycosides have comparable or higher antioxidant capacities than that of vitamin C.
Quercetin 4-glycoside is catabolized through ring fission by intestinal bacteria into phenolic acids, such as 3,4-dihydroxyphenylacetic acid, which has higher biological activities, such as antioxidant effects, than its parent molecule.
Furthermore, it has been reported that a relatively large portion of ingested rutin remains intact in the ileal fluid and that rutin metabolism occurs mainly via microbial biotransformation in the large intestine.
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The biosynthesis of kaempferol occurs in four major steps:
Phenylalanine is converted into 4-coumaroyl-CoA.
4-coumaroyl-CoA combines with three molecules of malonyl-coA to form naringenin chalcone (tetrahydroxychalcone) through the action of the enzyme chalcone synthase.
Naringenin chalcone is converted to naringenin and then a hydroxyl group is added to form dihydrokaempferol.
Dihydrokaempferol has a double bond introduced into it to form kaempferol.
The amino acid phenylalanine is formed from the Shikimate pathway, which is the pathway that plants use in order to make aromatic amino acids. This pathway is located in the plant plastid, and is the entry to the biosynthesis of phenylpropanoids.
The phenylpropanoid pathway is the pathway that converts phenylalanine into tetrahydroxychalcone.
Flavonols, including kaempferol, are products of this pathway.
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Phenylalanine
Coumaroyl
Malonyl
Naringenin
Chalcone
Hydroxyl
Dihydro
Kaempferol
RE: Beam Me Up