The ancient city of Misis was founded in the Neolithic age. The founder of the city of Misis is Mopsus, a famous seer. The ancient city of Misis is on the silk road route. Therefore, the city of Misis is a trade center and a very rich city. Especially in the 8th century, the Abbasid kingdom invested a lot in the city of Misis. Unfortunately until this day, many buildings in Misis city have been demolished.