I think you'd go with the first one! I would.

The asylum is such a fascinating setting. Some of the first comics I made (but never finished) was very much inspired by Fritz Lang's film, The Testament of Dr. Mabuse, from 1933 which features a lot of asylum action :)

P.S.
I tried to buy the comic to support you, but I'm in Denmark and it only seems to be shipping in the US.