Axolotl is known as walking fist, but it is not a fish, its an amphibian. Axolotl is 1,000 times more resistant to cancer mammals. They can regenerate pretty much anything in their bodies. They can their skin, jaws, tail, limbs, and cord. They can regenerate their spinal cord even after being cut, crushed or removed. They can regenerate part of the brain after being cut. They can also receive transplanted organs from each other and accept them without rejection. These powerful creatures can regenerate the same limbs more than 100 times, without showing any signs of scarring at the site of amputation. Scientists are hoping to replicate these features in humans. An axolotl remains in its larval form its entire life. These creatures they can reach adulthood even without undergoing metamorphosis. A single injection of iodine can turn young axolotl into adult salamanders. The axolotl's immune system is the primary factor in its regenerative ability. Immune cells called macrophages are critical in the early stages of regenerating lost limbs. The immune system's response to injury depends on macrophages cells. They arrive at the wound site within 2 to 4 days. They surround, digest the pathogens and then generate signals for healing. Macrophage cells were also detected at the wound in large numbers around 4 to 6 days after injury, with macrophages removed, the salamanders failed to generate new limbs and started showing substantial scarring in the tissues Those that had only some of their macrophages could still regenerate their limbs, but at much slower pace than normal. Once the salamanders replenished their macrophages level. The researchers re-amputated the animals' limbs stumps which fully regenerated at the normal rate.
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