Is it possible to go through the entirety of life without ever being depressed -- even just once?

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I don't see the possibility in that. people can handle depression in a better way but totally avoiding getting depressed seems impossible. life is not a bed of roses, there will always be ups and down and the human body will respond to stimulus based on things happening.

The fact that people don't go crazy while depressed or handle it well doesn't mean their life is void of depression.