When (depending on the path you chose for V) is running on borrowed time after the chip they stole during the heist with Jackie has Johnny Silverhand, who's slowly hurting V, they must find a solution as the relic malfunctions worsen.
In Cyberpunk 2077, you can choose 3 paths for V: Nomad, Streetkid, and Corpo. Each path has a different intro and introduces you to Jackie differently.
From @gamingwithme