• Asana.com : From the origianl CTO / Co-founder of Facebook, this has an excellent UI based on Lua script technology
• Airtable - this is another, suprisingly spreadsheet like tracker with cool features
• zoho : they have an entire suite of applications and free to start email service.

for software development

• a Favorite is Phabricator.org (used by Wikipedia, Blender, KDE, Facebook, Asana etc)
• GitLab is getting amazing