Haha when I started this comic 3-5 years ago I never imagined any part of the contagion aspect would be so topical XD

In my mind I had modeled it almost like nicotine addiction/resistance. If you're a smoker you can handle putting on a nicotine patch, you might even like it - but if you've never smoked, that patch (or smoking your first cigarette) will make you sick as hell.