Sugar stops Urinary Tract Infections by blocking adhesion of bacterial pathogen to host surfaces.
Good morning steemians!!!
Scientists say that Bacteria that cause Urinary Tract Infections adhere to host mucosal surfaces using CUP pilus. Studies dissecting the mechanism of adhesion of these filamentous structures to hosts identified D-linked mannose and O-linked mannose as the key host sugar moieties as the receptors for two key protein components of these pilus. And a synthetic mannoside M4284 that binds to these with greater affinity than D-Mannose clears and prevents infection by helping flush the gut and urinary tract of these adhesive bacteria.
