DMSO will carry through anything that's on your skin, so wash and dry your hands as well as the area being treated, then rewash your hands, leave the treated area uncovered for 20 minutes and you're done. Nothing scary or complicated. It's great for any sort of inflammation such as arthritis, for pulls and strains and knocks and bangs as well as for headaches. For inflammation, the secret is consistency. Don't do the treatment once or twice and declare it a failure. I was diagnosed with arthritis in my back and I cured it with DMSO. It took me 6 months of twice daily treatment though.
There are a couple of books available to download free that might interest you.
https://inancientfootsteps.com/wp-content/uploads/2024/02/The-Dmso-Handbook-for-Doctors-Archie-H.-Scott.pdf
https://reader.z-library.sk/read/8fc79300b97695f7c8bd17170744a32c33d5dbaba3684a7a3e68407361ef4d87/17448781/c49bb9/dmso-natures-healer.html

Don't hesitate to throw any questions my way.

Edit; Amandha Vollmer is a DMSO expert. You can see her beginner's class here
https://yummy.doctor/video-list/learning-about-dmso-a-beginner-class-with-amandha-vollmer-adv/